abstract：:Coronary no-reflow is defined as inadequate myocardial perfusion of a given coronary segment without angiographic evidence of mechanical vessel obstruction. No-reflow is visualized angiographically as a reduction in thrombolysis in myocardial infarction (TIMI) flow grade and is typically accompanied by chest pain, ele...

journal_title：Yonsei medical journal

authors： Son JW,Kim JS,Lee JM,Hong SJ,Jung MK,Kim DH,Kim JS,Choi D,Jang Y

更新日期：2010-07-01 00:00:00

abstract：PURPOSE:This study was designed to assess the prevalence and correlates of disturbed eating attitudes and behaviors in South Korean students. MATERIALS AND METHODS:In a cross-sectional survey, 2,226 fourth and seventh grade students filled out questionnaires on eating attitudes and behaviors (Eating Attitude Test -26,...

journal_title：Yonsei medical journal

authors： Yang SJ,Kim JM,Yoon JS

更新日期：2010-05-01 00:00:00

abstract：PURPOSE:The aim of this study was to determine whether retinol-binding protein 4 (RBP4), adiponectin and high molecular weight (HMW) adiponectin are associated with insulin resistance (IR) and metabolic parameters in non-diabetic hypertensive patients. Also, we sought to compare the predictive values of these adipocyto...

journal_title：Yonsei medical journal

authors： Shim CY,Park S,Kim JS,Shin DJ,Ko YG,Kang SM,Choi D,Ha JW,Jang Y,Chung N

更新日期：2010-05-01 00:00:00

abstract：:Bortezomib, an inhibitor of 26S proteosome, is recently approved treatment option for multiple myeloma. Thalidomide, a drug with immunomodulating and antiangiogenic effects, has also shown promise as an effective treatment in multiple myeloma. Pulmonary complications are believed to be rare, especially interstitial lu...

journal_title：Yonsei medical journal

authors： Kang W,Kim JS,Cho SH,Kim SK,Chang J,Park MS

更新日期：2010-05-01 00:00:00

abstract：PURPOSE:This study was undertaken to evaluate the long-term treatment of esophageal strictures in children with corrosive esophagitis and to determine the effect of self-bougienage on recurrent strictures. MATERIALS AND METHODS:We reviewed the medical records of nine children that were treated for corrosive esophageal...

journal_title：Yonsei medical journal

authors： Lee HJ,Lee JH,Seo JM,Lee SK,Choe YH

更新日期：2010-03-01 00:00:00

abstract：PURPOSE:The purpose of this study is to assess patient attitudes towards anti-glaucoma medication and their association with adherence, visual quality of life, and personality traits. MATERIALS AND METHODS:One hundred and forty-seven glaucoma patients were enrolled this study. The participants were divided into 'pharm...

journal_title：Yonsei medical journal

authors： Hong S,Kang SY,Yoon JU,Kang U,Seong GJ,Kim CY

更新日期：2010-03-01 00:00:00

abstract：PURPOSE:We investigated the association between the tryptohan hydroxylase 1 (TPH1) gene and aggression in schizophrenia in a Korean population. MATERIALS AND METHODS:The sample included 61 aggressive patients as well as 104 non-aggressive patients from psychiatric hospitals and 335 healthy volunteers in Korea. Blood s...

journal_title：Yonsei medical journal

authors： Kim YR,Lee JY,Min SK

更新日期：2010-01-01 00:00:00

abstract：PURPOSE:The purpose of this study is to evaluate the clinical results of treatment with a high dose of 3-dimensional conformal boost (3DCB) using a real-time tracking radiation therapy (RTRT) system in cervical cancer patients. MATERIALS AND METHODS:Between January 2001 and December 2004, 10 patients with cervical can...

journal_title：Yonsei medical journal

authors： Park HC,Shimizu S,Yonesaka A,Tsuchiya K,Ebina Y,Taguchi H,Katoh N,Kinoshita R,Ishikawa M,Sakuragi N,Shirato H

更新日期：2010-01-01 00:00:00

abstract：:Eosinophilic gastroenteritis (EG) is characterized by eosinophilic infiltration of the bowel wall and variable gastrointestinal manifestations. Clinicians should have a high index of suspicion for EG when faced with gastrointestinal symptoms and peripheral eosinophilia to avoid incorrect diagnosis and inappropriate tr...

journal_title：Yonsei medical journal

authors： Cha JM,Lee JI,Joo KR,Shin HP

更新日期：2010-01-01 00:00:00

abstract：PURPOSE:Physicians and oncology nurses must continue to update their knowledge on treatment and treatment-related side effects, while searching for effective methods to prevent or manage side effects. The objective of our study was to describe the incidence and response to treatment of the hand-foot syndrome (HFS) and ...

journal_title：Yonsei medical journal

authors： Son HS,Lee WY,Lee WS,Yun SH,Chun HK

更新日期：2009-12-31 00:00:00

abstract：:Coronary-subclavian steal through the left internal mammary graft is a rare cause of myocardial ischemia in patients who have had a coronary bypass surgery. We report a 70-year-old man who presented with sustained monomorphic ventricular tachycardia 5 years after the surgical creation of a left internal mammary to the...

journal_title：Yonsei medical journal

authors： Kursaklioglu H,Kose S,Iyisoy A,Amasyali B,Celik T,Aytemir K,Isik E

更新日期：2009-12-31 00:00:00

abstract：PURPOSE:To observe changes in audiology, intellectual development, behavior development, and physical growth during systematic follow-up of infants with asymptomatic congenital human cytomegalovirus (HCMV) infection. MATERIALS AND METHODS:Fifty-two infants diagnosed with asymptomatic congenital HCMV infection from Jul...

journal_title：Yonsei medical journal

authors： Shan R,Wang X,Fu P

更新日期：2009-10-31 00:00:00

abstract：:Tracheobronchopathia osteochondroplastica (TO) is a rare disorder of unknown cause characterized by the presence of multiple submucosal osseous and/or cartilaginous nodules that protrude into the lumen of the trachea and large bronchi. A simultaneous diagnosis of TO and amyloidosis is rarely reported. In this report, ...

journal_title：Yonsei medical journal

authors： Kirbaş G,Dağli CE,Tanrikulu AC,Yildiz F,Bükte Y,Senyiğit A,Kiyan E

更新日期：2009-10-31 00:00:00

abstract：PURPOSE:To describe the therapeutic effect and possibility of the ultra-early surgery for poor-grade aneurysmal subarachnoid hemorrhage (Hunt-Hess grades IV-V). MATERIALS AND METHODS:Nine cases with intracranial aneurysms, demonstrated by computed tomographic angiography (CTA), were treated by ultra-early surgery unde...

journal_title：Yonsei medical journal

authors： Pan JW,Zhan RY,Wen L,Tong Y,Wan S,Zhou YY

更新日期：2009-08-31 00:00:00

abstract：:Although cysticercosis is the most common parasitic disease affecting the central nervous system, spinal cysticercosis is rare. A rare form of spinal cysticercosis involving the whole spinal canal is presented. A 45-year-old Korean male had a history of intracranial cysticercosis and showed progressive paraparesis. Sp...

journal_title：Yonsei medical journal

authors： Shin DA,Shin HC

更新日期：2009-08-31 00:00:00

abstract：:Colorectal cancers (CRC)--and probably all cancers--are caused by alterations in genes. This includes activation of oncogenes and inactivation of tumor suppressor genes (TSGs). There are many ways to achieve these alterations. Oncogenes are frequently activated by point mutation, gene amplification, or changes in the ...

journal_title：Yonsei medical journal

authors： Boland CR,Shin SK,Goel A

更新日期：2009-06-30 00:00:00

abstract：PURPOSE:The most important function of the larynx is airway protection which is provided through a polysynaptic reflex closure triggered by the receptors in the glottic and supraglottic mucosa, evoking the reflex contraction of the laryngeal muscles especially by strong adduction of vocal cords. Based on the hypotheses...

journal_title：Yonsei medical journal

authors： Kim YH,Kang JW,Kim KM

更新日期：2009-06-30 00:00:00

abstract：:Isotretinoin is a known human teratogen that can cause multiple malformations. At present, women who conceive one cycle after discontinuing isotretinoin are told that their teratogenic risk is not higher than baseline. We present a case of both-ear malformation in a newborn whose mother had taken isotretinoin for 2 ye...

journal_title：Yonsei medical journal

authors： Lee SM,Kim HM,Lee JS,Yoon CS,Park MS,Park KI,Namgung R,Lee C

更新日期：2009-06-30 00:00:00

abstract：PURPOSE:This study aimed to determine the impaired glucose tolerance and diabetes prevalence in patients with essential hypertension (HT) and to compare the developed microvascular complications of these groups. MATERIALS AND METHODS:An oral glucose tolerance test (OGTT) was performed on 338 essential hypertensive cas...

journal_title：Yonsei medical journal

authors： Tugrul A,Guldiken S,Ugur-Altun B,Arikan E

更新日期：2009-04-30 00:00:00

abstract：PURPOSE:To evaluate the diagnosis and treatment of the carpal tunnel syndrome (CTS) due to space occupying lesions (SOL). MATERIALS AND METHODS:Eleven patients and 12 cases that underwent surgery for CTS due to SOL were studied retrospectively. We excluded SOL caused by bony lesions, such as malunion of distal radius ...

journal_title：Yonsei medical journal

authors： Kang HJ,Jung SH,Yoon HK,Hahn SB,Kim SJ

更新日期：2009-04-30 00:00:00

abstract：:This study aimed to identify the association between gamma-aminobutyric acid-A (GABA-A) receptor subunit beta3 (GABRB3) gene and autism spectrum disorders (ASD) in Korea. Fifty-eight children with ASD [47 boys (81.0%), 5.5 +/- 4.1 years old], 46 family trios, and 86 healthy control subjects [71 males (82.6%), 33.6 +/-...

journal_title：Yonsei medical journal

authors： Yoo HK,Chung S,Hong JP,Kim BN,Cho SC

更新日期：2009-04-30 00:00:00

abstract：PURPOSE:Techniques designed to identify differentially expressed genes (DEGs) in tumors have become important in modern pathology. Genefishing technique using the annealing control primer (ACP) system has recently been developed to screen for DEG transcripts. We tried to identify DEGs involved in papillary thyroid canc...

journal_title：Yonsei medical journal

authors： Lee KY,Huang SM,Li S,Kim JM

更新日期：2009-02-28 00:00:00

abstract：PURPOSE:Genetic factors are known to be important in the etiology of bipolar disorder (BD). The fragile sites (FSs) are a very interesting subject for the study of clinical disorders. The aim of this study was to evaluate fragile sites seen in patients with bipolar disorder and find a correlation between some fragile s...

journal_title：Yonsei medical journal

authors： Demirhan O,Tastemir D,Sertdemir Y

更新日期：2009-02-28 00:00:00

abstract：PURPOSE:Genes of the HoxD cluster play a major role in vertebrate limb development, and changes that modify the Hoxd12 locus affect other genes also, suggesting that HoxD function is coordinated by a control mechanism involving multiple genes during limb morphogenesis. In this study, mutant phenotypes were produced by ...

journal_title：Yonsei medical journal

authors： Cho KW,Kim JY,Cho JW,Cho KH,Song CW,Jung HS

更新日期：2008-12-31 00:00:00

abstract：:Epithelioid hemangioendothelioma (EHE) is a rare tumor of vascular origin. While it can be found in any tissue, it is most often found in lung and liver and usually has an intermediate behavior. EHEs originating from pleural tissue have been less frequently described than those from other sites. Furthermore, to date, ...

journal_title：Yonsei medical journal

authors： Lee YJ,Chung MJ,Jeong KC,Hahn CH,Hong KP,Kim YJ,Kim YT

更新日期：2008-12-31 00:00:00

abstract：:Robotic colorectal surgery has gradually been performed more with the help of the technological advantages of the da Vinci system. Advanced technological advantages of the da Vinci system compared with standard laparoscopic colorectal surgery have been reported. These are a stable camera platform, three-dimensional im...

journal_title：Yonsei medical journal

authors： Baik SH

更新日期：2008-12-31 00:00:00

abstract：PURPOSE:The aim of this study was to evaluate the efficacy of low-dose oral methotrexate (MTX) as a treatment for patients with Kawasaki disease (KD) which was resistant to intravenous immunoglobulin (IVIG). PATIENTS AND METHODS:The patients who had persistent or recrudescent fever after treatment with IVIG were subse...

journal_title：Yonsei medical journal

authors： Lee TJ,Kim KH,Chun JK,Kim DS

更新日期：2008-10-31 00:00:00

abstract：PURPOSE:To provide a systematic review with meta-analysis for addressing the relationship between fecal bile acids (FBAs) and colorectal cancer. MATERIALS AND METHODS:Electronic databases were searched for all observational studies that examined the relationship between FBAs and colorectal cancer or adenoma, and calcu...

journal_title：Yonsei medical journal

authors： Tong JL,Ran ZH,Shen J,Fan GQ,Xiao SD

更新日期：2008-10-31 00:00:00

abstract：:Extranodal marginal zone lymphoma is a low-grade B cell lymphoma that presents with an indolent clinicopathologic nature. Although this tumor can occur in various sites, including the gastrointestinal tract and lungs, it develops and spreads extremely rarely along the trachea and central airway. We report a case of ex...

journal_title：Yonsei medical journal

authors： Kang JY,Park HJ,Lee KY,Lee SY,Kim SJ,Park SH,Kim YK

更新日期：2008-10-31 00:00:00

abstract：PURPOSE:We developed a numerical model that predicts cardiovascular system response to hemodialysis, focusing on the effect of sodium profile during treatment. MATERIALS AND METHODS:The model consists of a 2-compartment solute kinetics model, 3-compartment body fluid model, and 12-lumped-parameter representation of th...

journal_title：Yonsei medical journal

authors： Lim KM,Choi SW,Min BG,Shim EB

更新日期：2008-08-30 00:00:00

abstract：:Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominantly inherited syndrome. MEN1 is characterized by the presence of functioning and nonfunctioning tumors or hyperplasia of the pituitary gland, parathyroid glands, and pancreatic islet cells. In addition, MEN1 carriers can have adrenal or thyroid tumors a...

journal_title：Yonsei medical journal

authors： Choi H,Kim S,Moon JH,Lee YH,Rhee Y,Kang ES,Ahn CW,Cha BS,Lee EJ,Kim KR,Lee HC,Jeong SY,Kim HJ,Lim SK

更新日期：2008-08-30 00:00:00

abstract：PURPOSE:Although many studies have demonstrated improvements in short-and long-term outcomes of gastric cancer surgery, changes in long-term survival over time are not well-established. This study was conducted to evaluate changes in host, tumor, and treatment factors in patients treated at a single institution over a ...

journal_title：Yonsei medical journal

authors： Hyung WJ,Kim SS,Choi WH,Cheong JH,Choi SH,Kim CB,Noh SH

更新日期：2008-06-30 00:00:00

abstract：PURPOSE:To investigate the effect of ultra low molecular weight heparin (ULMWH) on glutamate induced apoptosis in rat cortical cells and to explore the possible mechanisms. MATERIALS AND METHODS:Cell viability was measured using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. Apoptosis was first an...

journal_title：Yonsei medical journal

authors： Yu TG,Zhang QZ,Zhang ZG,Wang WW,Ji SL,Du GH

更新日期：2008-06-30 00:00:00

abstract：PURPOSE:The precise molecular mechanisms culminating in coronary artery disease (CAD) are not well understood, despite a wealth of knowledge on predisposing risk factors and pathomechanisms. CAD and myocardial infarction (MI) are complex genetic diseases; neither the environment alone, nor a single gene, cause disease,...

journal_title：Yonsei medical journal

authors： Ercan B,Tamer L,Sucu N,Pekdemir H,Camsari A,Atik U

更新日期：2008-04-30 00:00:00

abstract：PURPOSE:The sarco/endoplasmic reticulum Ca2+-ATPase (SERCA), encoded by ATP2A2, is an essential component for G-protein coupled receptor (GPCR)-dependent Ca2+ signaling. However, whether the changes in Ca2+ signaling and Ca2+ signaling proteins in parotid acinar cells are affected by a partial loss of SERCA2 are not kn...

journal_title：Yonsei medical journal

authors： Choi JH,Jo H,Hong JH,Lee SI,Shin DM

更新日期：2008-04-30 00:00:00

abstract：PURPOSE:Activation of the innate immune system and chronic low-grade inflammation are thought to be involved in the pathogenesis of atherosclerosis and also thought to be associated with type 2 diabetes and its complications. As a receptor for bacterial lipopolysaccharide and heat-shock proteins, Toll-like receptor 4 (...

journal_title：Yonsei medical journal

authors： Kim YS,Hwang YJ,Kim SY,Yang SM,Lee KY,Park IeB

更新日期：2008-02-29 00:00:00

abstract：PURPOSE:Plasma levels of renin, angiotensin II and aldosterone are increased during normal pregnancy. However, these values in preeclampsia are decreased to nearly that of a nonpregnant subject, and vascular sensitivity to angiotensin II is increased. In preeclampsia, aldosterone is decreased less than rennin. Therefor...

journal_title：Yonsei medical journal

authors： Kim EH,Lim JH,Kim YH,Park YW

更新日期：2008-02-29 00:00:00

abstract：PURPOSE:The current methods used to evaluate the efficacy of drug products are inadequate. We propose a non-inferiority approach to prove the safety of drugs. MATERIALS AND METHODS:Traditional hypotheses for the evaluation of the safety of drugs are based on proof of hazard, which have proven to be inadequate. Therefo...

journal_title：Yonsei medical journal

authors： Liu JP

更新日期：2007-12-31 00:00:00

abstract：PURPOSE:In order to improve the likelihood of curative and safe gastric surgery, this study investigated the clinical features and surgical outcomes of gastric cancer with a synchronous cancer. PATIENTS AND METHODS:The clinicopathological data of 10,090 gastric cancer patients at Samsung Medical Center from September ...

journal_title：Yonsei medical journal

authors： Ha TK,An JY,Youn HG,Noh JH,Sohn TS,Kim S

更新日期：2007-12-31 00:00:00

abstract：:A 44-year-old woman underwent surgery for an asymptomatic primary tumor of the heart located in the right atrium. The tumor was detected incidentally during follow-up computed tomography for a resected breast cancer. The mass, lying along the lower portion of the right atrial septum, was homogenous and cystic in natur...

journal_title：Yonsei medical journal

authors： Kim SJ,Shin ES,Kim SW,Shin JK,Cheong JP,Kim YM,Lee SG

更新日期：2007-12-31 00:00:00